Effects of Particulate Matter in a Mouse Model of Oxazolone-Induced Atopic Dermatitis.
Yoo Jung BaeKui Young ParkHye Sung HanYoung Shin KimJi-Yeon HongTae Young HanSeong Jun SeoPublished in: Annals of dermatology (2020)
In conclusion, we found that PM aggravates skin barrier dysfunction, clinically augmenting epidermal and dermal thickening with dermal inflammation in AD-like skin. These results suggest that PM may trigger the exacerbation of AD symptoms via skin barrier dysfunction-related mechanisms.
Keyphrases
- particulate matter
- wound healing
- air pollution
- oxidative stress
- soft tissue
- mouse model
- atopic dermatitis
- chronic obstructive pulmonary disease
- diabetic rats
- drug induced
- heavy metals
- polycyclic aromatic hydrocarbons
- depressive symptoms
- risk assessment
- intensive care unit
- physical activity
- mechanical ventilation
- sleep quality