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Quiescent ovarian cancer cells secrete follistatin to induce chemotherapy resistance in surrounding cells in response to chemotherapy.

Alexander J ColeSantiago Panesso-GomezJaynish S ShahTonge EbaiQi JiangEce GumusogluMaya G BelloAnda M VladFrancesmary ModugnoRobert P EdwardsRonald J Buckanovich
Published in: Clinical cancer research : an official journal of the American Association for Cancer Research (2023)
FST is a novel therapeutic target to improve OvCa response to chemotherapy and potentially reduce recurrence rates.
Keyphrases
  • locally advanced
  • induced apoptosis
  • squamous cell carcinoma
  • cell cycle arrest
  • rectal cancer
  • radiation therapy
  • oxidative stress
  • signaling pathway