mtIF3 is locally translated in axons and regulates mitochondrial translation for axonal growth.
Soyeon LeeDongkeun ParkChunghun LimJae-Ick KimKyung-Tai MinPublished in: BMC biology (2022)
We describe a previously unknown function of mitochondrial initiation factor 3 (mtIF3) in axonal protein synthesis and development. These findings provide insight into the way neurons adaptively control mitochondrial physiology and axonal development via local mtIF3 translation.