Structural and Functional Brain Imaging in Long-Term Survivors of Childhood Acute Lymphoblastic Leukemia Treated With Chemotherapy: A Systematic Review.
Kellen GandyMatthew A ScogginsLisa M JacolaMolly LittenWilburn E ReddickKevin R KrullPublished in: JNCI cancer spectrum (2021)
Although the neurotoxic effects of cancer treatment are reduced in the absence of cranial radiation, survivors treated on chemotherapy-only protocols still display long-term alterations in brain structure and function, which contribute to lifelong neurocognitive late effects.
Keyphrases
- acute lymphoblastic leukemia
- resting state
- white matter
- young adults
- locally advanced
- high resolution
- functional connectivity
- cerebral ischemia
- bipolar disorder
- allogeneic hematopoietic stem cell transplantation
- squamous cell carcinoma
- multiple sclerosis
- mass spectrometry
- childhood cancer
- brain injury
- blood brain barrier
- acute myeloid leukemia