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Investigating the Lowest Threshold of Vascular Benefits from LDL Cholesterol Lowering with a PCSK9 mAb Inhibitor (Alirocumab) in Patients with Stable Cardiovascular Disease (INTENSITY-HIGH): protocol and study rationale for a randomised, open label, parallel group, mechanistic study.

Paul J CacciottoloMichalis S KostapanosElena Hernan SanchoHolly PaveyFotini KaloyirouEvangelia VamvakaJoanna HelmyAnnette HubschCarmel M McEnieryIan B WilkinsonJoseph Cheriyan
Published in: BMJ open (2021)
NCT03355027.
Keyphrases
  • open label
  • cardiovascular disease
  • clinical trial
  • low density lipoprotein
  • type diabetes
  • study protocol
  • squamous cell carcinoma
  • high intensity
  • double blind
  • placebo controlled