An evaluation of mitapivat for the treatment of hemolytic anemia in adults with pyruvate kinase deficiency.

Published in: Expert review of hematology (2022)

R479H mutation. Further investigations are needed regarding long-term safety and efficacy profiles and whether long-term PKD-associated complications can be reduced or even reversed.

Keyphrases

chronic kidney disease
risk factors
tyrosine kinase
protein kinase
iron deficiency