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Prophylactic Administration of Diphenhydramine/Acetaminophen and Ondansetron Reduced Postoperative Nausea and Vomiting and Pain Following Laparoscopic Sleeve Gastrectomy: a Randomized Controlled Trial.

Pejman PourfakhrMojtaba AghabagheriHossein Zabihi MahmoudabadiKhosrow NajjariMohammad TalebpourMohammad Reza Khajavi
Published in: Obesity surgery (2021)
Prophylactic diphenhydramine 0.4 mg/kg at the induction of general anesthesia in combination with acetaminophen 1 g and ondansetron 4 mg at the end of surgery reduced the incidence of PONV and postoperative severity of pain in laparoscopic sleeve gastrectomy.
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