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Relationships of surrogate indexes of insulin resistance with insulin sensitivity assessed by euglycemic hyperinsulinemic clamp and subclinical vascular damage.

Teresa Vanessa FiorentinoMaria Adelaide MariniElena SuccurroFrancesco AndreozziGiorgio Sesti
Published in: BMJ open diabetes research & care (2019)
Among the surrogate TG/HDL-C ratio, VAI, LAP and TyG indexes of insulin sensitivity, LAP index showed a significant association with insulin-stimulated glucose disposal across the different glucose tolerance categories and the highest ability to detect insulin resistance and subclinical vascular damage.
Keyphrases
  • insulin resistance
  • type diabetes
  • adipose tissue
  • high fat diet
  • metabolic syndrome
  • polycystic ovary syndrome
  • oxidative stress
  • skeletal muscle
  • glycemic control
  • high fat diet induced
  • blood pressure