Long-Read Sequencing with Hierarchical Clustering for Antiretroviral Resistance Profiling of Mixed Human Immunodeficiency Virus Quasispecies.

Timothy Ting-Leung NgJunhao SuHiu-Yin LaoWui-Wang LuiChloe Toi-Mei ChanAmy Wing-Sze LeungStephanie Hoi-Ching JimLam-Kwong LeeSheeba ShehzadKingsley King-Gee TamKenneth Siu-Sing LeungForrest TangWing-Cheong YamRuibang LuoGilman Kit-Hang Siu

Published in: Clinical chemistry (2023)

Long-read sequencing coupled with hierarchical clustering could differentiate the quasispecies resistance profiles in HIV-infected samples, providing a clearer picture for medical care.

Keyphrases

human immunodeficiency virus
hiv infected
single cell
antiretroviral therapy
rna seq
hepatitis c virus
hiv positive
hiv aids
hiv infected patients
single molecule