NanoString-based breast cancer risk prediction for women with sclerosing adenosis.

Stacey J WinhamChristine MehnerEthan P HeinzenBrendan T BroderickMelody Stallings-MannAziza NassarRobert A VierkantTanya L HoskinRyan D FrankChen WangLori A DenisonCeline M VachonMarlene H FrostLynn C HartmannE Aubrey ThompsonMark E ShermanDaniel W VisscherAmy C DegnimDerek C Radisky

Published in: Breast cancer research and treatment (2017)

Our results demonstrate that biomarkers of breast cancer risk can be detected in benign breast tissue years prior to cancer development in women with SA. These markers can be assessed using assay methods optimized for RNA derived from FFPE biopsy tissues which are commonly available.

Keyphrases

breast cancer risk
papillary thyroid
gene expression
squamous cell
high throughput
ultrasound guided
fine needle aspiration
nucleic acid
single cell