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[Registry-based comparison of multiple sclerosis epidemiology trend data in 1999 and 2019: the case of Yaroslavl].

N N SpirinD S KasatkinI O StepanovE G ShipovaN V BaranovaT V VinogradovaS S MolchanovaD V KiselevV A ShadrichevN N SpirinaD A Kachura
Published in: Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova (2020)
Clinical and epidemiological review of Yaroslavl MS Registry data in 1999 and 2019 showed significant changes in disease pattern. The prevalence rate increased from 42.6 to 78.5 cases per 100,000 people. The morbidity rate rose from 1.58 to 3.28 cases per 100,000 people. The reasons for the increase are improvement in the diagnostic quality, new diagnostic criteria and the true growth of prevalence and morbidity. The use of disease modifying drugs (DMDs) has extended «the time to EDSS 3,0» by 4 years, «the time to EDSS 6,0» by 5-8 years.
Keyphrases
  • multiple sclerosis
  • risk factors
  • electronic health record
  • big data
  • mass spectrometry
  • ms ms
  • white matter
  • data analysis
  • machine learning
  • artificial intelligence
  • deep learning