Repertoire analysis of memory T-cell receptors in Japanese patients with inflammatory bowel disease.
Yoichi KakutaTakeru NakanoTakeo NaitoKazuhiro WatanabeYasuhiro IzumiyamaDaisuke OkamotoRyo IchikawaRintaro MoroiMasatake KurohaYoshitake KanazawaTomoya KimuraHisashi ShigaTakeshi NaitohYoshitaka KinouchiMichiaki UnnoAtsushi MasamunePublished in: JGH open : an open access journal of gastroenterology and hepatology (2020)
The diversity of TCR clones in LPMCs and PBMCs in patients with IBD was significantly lower than that of PBMCs in controls. TCR diversity in PBMCs was particularly low in patients with CD.