Recombinant CsHscB of carcinogenic liver fluke Clonorchis sinensis induces IL-10 production by binding with TLR2.

Chao YanFan FangYu-Zhao ZhangXin DongJing WuHai-Liang LiuChun-Yang FanStephane KodaBei-Bei ZhangQian YuLiang WangYu-Gang WangJia-Xu ChenKui-Yang Zheng

Published in: PLoS neglected tropical diseases (2020)

Our data thus demonstrate that rCsHscB from C. sinensis interacts with TLR2 to be endowed with immune regulatory activities, and may have some therapeutic implications in future beyond parasitology.

Keyphrases

toll like receptor
inflammatory response
immune response
binding protein
nuclear factor
electronic health record
current status
transcription factor
big data
cell free
dna binding
polycyclic aromatic hydrocarbons
data analysis