Aging Cartilage in Wild-Type Mice: An Observational Study.
Joulnar AkoumKhadija TahiriMarie-Thérèse CorvolDidier BorderieFrançois ÉtienneFrançois RannouChristelle NguyenPublished in: Cartilage (2020)
C57BL/6-JRj wild-type male mice showed continuously increasing osteoarthritic changes but delayed decreasing walking speed with age. These variations were maximal between 3 and 9 months of age. Maximal serum CTX-II content preceded these changes.