Diagnostic performance of perilesional radiomics analysis of contrast-enhanced mammography for the differentiation of benign and malignant breast lesions.

• Radiomics analysis of the annular perilesional region of 3 mm in CEM images may provide valuable information for the differential diagnosis of benign and malignant breast lesions. • The radiomics information from the lesion region and the annular perilesional region may be complementary. Combining the predicted probabilities of the models constructed by the features from the two regions may improve the diagnostic performance of radiomics models.