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Association of genetic polymorphism of PC-1 gene (rs1044498 Lys121Gln) with insulin-resistant type 2 diabetes mellitus in Punjabi Population of Pakistan.

Abdullah Abdo AlbegaliMuhammad ShahzadMuhammad Ikram UllahSaqib MahmoodMaryam Rashid
Published in: Molecular genetics & genomic medicine (2019)
Overall, the results indicate that the K121Q polymorphism was not found associated with insulin resistance in type 2 diabetes in a Pakistani Punjabi population. This is the first-ever report about the genotype of PC-1 gene in this population.
Keyphrases
  • type diabetes
  • glycemic control
  • genome wide
  • copy number
  • dna methylation
  • insulin resistance
  • metabolic syndrome
  • genome wide identification
  • transcription factor
  • adipose tissue
  • cardiovascular risk factors