Molecular nanoarchitectonics of proton triggered tetraphenylethylene-based detector: colorimetric, reversible, and intracellular pH.
Harshad A MirganeKerba S MoreAmbadas B RodeAvinash L PuyadSheshanath V BhosalePublished in: Analytical methods : advancing methods and applications (2023)
In this paper, we designed, synthesized, and characterized 4,4',4'',4'''-(ethene-1,1,2,2-tetrayl)tetrakis( N , N -dimethylaniline) (1). Furthermore, UV-Vis absorbance and fluorescence emission studies reveal that 1 acts as a selective and sensitive probe for reversible acid-base sensing in solution as well as in the solid state. Nevertheless, the probe exhibited colorimetric sensing and intracellular fluorescent cell imaging of acid-base sensitive cells, making it a practical sensor with several potential applications in chemistry.
Keyphrases
- living cells
- solid state
- single molecule
- fluorescent probe
- quantum dots
- gold nanoparticles
- single cell
- sensitive detection
- induced apoptosis
- hydrogen peroxide
- reactive oxygen species
- cell cycle arrest
- high resolution
- genome wide
- aqueous solution
- cell therapy
- cell death
- endoplasmic reticulum stress
- magnetic resonance imaging
- oxidative stress
- magnetic resonance
- dna methylation
- human health
- computed tomography
- risk assessment
- case control
- photodynamic therapy
- pi k akt