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Family Recall of and Response to Germline Pathologic Variants Found on Paired Tumor-Germline Sequencing in Pediatric Oncology.

Michelle F JacobsJoshua W GoldmanSarah AustinErika S KoeppeAndrea M MuradCarl J KoschmannArul M ChinnaiyanRajen J Mody
Published in: JCO precision oncology (2024)
While most respondents remembered that a GPV was identified in the patient, some did not recall having a GPV found, and others recalled germline findings incorrectly. Future work may determine patient/family preferences for timing/method of result return to optimize patient recall and use of germline results.
Keyphrases
  • dna repair
  • case report
  • palliative care
  • squamous cell carcinoma
  • single cell
  • neoadjuvant chemotherapy
  • gene expression
  • oxidative stress
  • decision making