Epigenetic programming underpins B-cell dysfunction in peanut and multi-food allergy.

Samira ImranMelanie R NeelandJennifer KoplinShyamali DharmageMimi Lk TangSusan SawyerThanh DangVicki McWilliamRachel PetersKirsten P PerrettBoris NovakovicRichard Saffery

Published in: Clinical & translational immunology (2021)

Our data highlight epigenetic changes in B cells associated with peanut allergy, distinguishing features of the epigenome between single-food- and multi-food-allergic individuals and revealing differential developmental pathways potentially underpinning these distinct phenotypes.

Keyphrases

dna methylation
gene expression
human health
oxidative stress
big data
risk assessment
machine learning
allergic rhinitis
climate change