Clinical validation of 13-gene DNA methylation analysis in oral brushing samples for detection of oral carcinoma: Italian multicenter study.

Davide Bartolomeo GissiLuca MorandiGiuseppe ColellaRoberto De LucaGiuseppina CampisiRodolfo MauceriUmberto RomeoGianluca TenoreMichele D MignognaDaniela AdamoGiacomo OteriAntonia MarcianòPaolo VescoviMarco MeletiRosario SerpicoDario Di StasioMonica PenteneroAndrea SantarelliAlberto BianchiSalvatore CrimiClaudio MarchettiAchille TarsitanoMaria Pia FoschiniLucio Montebugnoli

Published in: Head & neck (2021)

These data confirmed the diagnostic performance of our novel procedure in a large cohort of brushing specimens collected from 11 different centers and analyzed in blindness.

Keyphrases

dna methylation
genome wide
copy number
gene expression
big data
machine learning
transcription factor
artificial intelligence
genome wide identification
clinical evaluation