Card9/neutrophil signalling axis promotes IL-17A-mediated ankylosing spondylitis.

Holly L RosenzweigEmily E VanceKofi Asare-KonaduKylie V KoneyEllen J LeeAtul A DeodharRouhin SenLiron CaplanRuth J Napier

Published in: Annals of the rheumatic diseases (2023)

These data reveal a novel neutrophil-intrinsic role for Card9 in arthritogenic Th17 responses and AS pathogenesis. These data provide valuable utility in our future understanding of CARD9-specific mechanisms in spondyloarthritis .

Keyphrases

ankylosing spondylitis
disease activity
rheumatoid arthritis
electronic health record
big data
systemic lupus erythematosus
current status
machine learning
artificial intelligence