SPHINGOSINE-1-PHOSPHATE/TGF- β AXIS DRIVES EPITHELIAL MESENCHYMAL TRANSITION IN ASTHMA-LIKE DISEASE.

Maria A RiemmaIda CerquaBarbara RomanoElena IrolloAntonio BertolinoRosa CamerlingoElisabetta GranatoGiuseppina ReaStefania ScalaMichela TerlizziGiuseppe SpazianoRosalinda SorrentinoBruno D'AgostinoFiorentina RoviezzoGiuseppe Cirino

Published in: British journal of pharmacology (2021)

Targeting S1P/TGF-β axis may hold promise as a feasible therapeutic target to control airway dysfunction in asthma.

Keyphrases

transforming growth factor
epithelial mesenchymal transition
chronic obstructive pulmonary disease
lung function
allergic rhinitis
signaling pathway
oxidative stress
big data
cancer therapy
air pollution
cystic fibrosis
drug delivery