Severity of non-alcoholic steatohepatitis is not linked to testosterone concentration in patients with type 2 diabetes.

Kristin Alexandra Dayton Fernando BrilDiana BarbJinping LaiSrilaxmi KalavalapalliKenneth Cusi

Published in: PloS one (2021)

NAFLD is linked to lower total testosterone in patients with T2DM, but likely given a common soil of insulin resistance/obesity and not from the severity of liver necroinflammation or fibrosis. Nevertheless, clinicians should consider screening patients with T2DM and NAFLD for hypogonadism.

Keyphrases

insulin resistance
replacement therapy
metabolic syndrome
high fat diet induced
adipose tissue
glycemic control
type diabetes
high fat diet
skeletal muscle
smoking cessation
polycystic ovary syndrome
weight loss
palliative care
liver injury
physical activity