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Novel mitochondrial and cytosolic purification pipeline for compartment-specific metabolomics in mammalian disease model tissues.

Gunter van der WaltRoan Louw
Published in: Metabolomics : Official journal of the Metabolomic Society (2020)
This study provides a simple and flexible solution for mitochondrial and cytosolic metabolomics in animal model tissues, towards large-scale application of such methodologies in disease research.
Keyphrases
  • oxidative stress
  • mass spectrometry
  • gene expression