Caseous necrosis of the mitral annulus: a new feature of drug-induced valvular heart disease? Case series.
Tiphaine LeblonClemence RioletPierre Vladimir EnnezatSylvestre MarechauxPublished in: European heart journal. Case reports (2021)
Prospective follow-up over several years of these two patients who initially had typical DI-VHD findings provided monitoring evidence of extensive calcifications and subsequent caseous necrosis. These reports suggest a link between calcific heart injury and benfluorex exposure. The diagnosis of DI-VHD may be overlooked at this late stage.
Keyphrases
- drug induced
- liver injury
- atrial fibrillation
- adverse drug
- aortic valve
- biofilm formation
- mitral valve
- left atrial
- left ventricular
- heart failure
- machine learning
- pulmonary hypertension
- aortic stenosis
- staphylococcus aureus
- transcatheter aortic valve replacement
- pseudomonas aeruginosa
- emergency department
- escherichia coli
- oral anticoagulants
- cystic fibrosis
- coronary artery disease