Bloodstream infection by multidrug-resistant Streptococcus oralis in a leukemic patient with febrile neutropenia after hematopoietic stem cell transplantation.
Noriyuki WatanabeKiyoko KobayashiSachie KoyamaMayu TabiraJunpei MatsunoYoshitada TajiYu AkuzawaMaho IshikawaTomoya MaedaKazuo ImaiNorihito TarumotoNorio AsouKotaro MitsutakeYasuhiro EbiharaPublished in: Transplant infectious disease : an official journal of the Transplantation Society (2020)
We reported the case of a patient with leukemia who developed febrile neutropenia after hematopoietic stem cell transplantation. Blood culture results revealed the presence of Streptococcus oralis, while antimicrobial susceptibility testing showed the resistance to penicillin and cephem. Furthermore, isolates were not susceptible to either meropenem or daptomycin but not to vancomycin. S oralis is known to belong to Streptococcus mitis group and be a causative agent of bacteremia in the neutropenic patients, but multidrug resistance of S oralis is rare. Our findings suggest that we might pay attention to the emergence of the microorganisms acquiring multidrug resistance in neutropenic patients.
Keyphrases
- end stage renal disease
- multidrug resistant
- acute myeloid leukemia
- ejection fraction
- chronic kidney disease
- newly diagnosed
- gram negative
- peritoneal dialysis
- case report
- candida albicans
- prognostic factors
- methicillin resistant staphylococcus aureus
- bone marrow
- biofilm formation
- drug resistant
- chemotherapy induced
- staphylococcus aureus
- working memory
- patient reported outcomes
- genetic diversity