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Drug Distribution in Living Cells via Label-Free Molecular Fingerprint.

Samir F El-Mashtoly
Published in: Journal of medicinal chemistry (2020)
A new application of stimulated Raman scattering (SRS) uses the benefit of a label-free molecular fingerprint to image the uptake and distribution of an alkyne-based drug in living cells. This method delivers information on cellular molecular composition and drug-cell interaction, showing the potential of SRS in drug development.
Keyphrases
  • label free
  • living cells
  • single molecule
  • fluorescent probe
  • adverse drug
  • single cell
  • healthcare
  • stem cells
  • cell therapy
  • emergency department
  • machine learning
  • quality control
  • climate change
  • human health
  • monte carlo