End-Truncated LAMB1 Causes a Hippocampal Memory Defect and a Leukoencephalopathy.
Chaker AlouiDominique HervéGaelle MarenneFlorian SavenierKilan Le GuennecFrancoise BergamettiEdgard VerduraThomas E LudwigJessica LebenbergWaliyde JabeurHélène MorelThibault CosteGeneviève DemarquayPanagiotis BachoumasJulien CogezGuillaume MatheyEmilien Bernardnull nullHugues ChabriatEmmanuelle GéninElisabeth Tournier-LasservePublished in: Annals of neurology (2021)
These findings are important for diagnosis and clinical care, to avoid unnecessary and sometimes invasive investigations, and also from a mechanistic point of view to understand the role of extracellular matrix proteins in neuronal homeostasis. ANN NEUROL 2021;90:962-975.