Intake of aspirin prior to metamizole does not completely prevent high on treatment platelet reactivity.
Christian PfrepperCarolin DietzeYvonne RemaneThilo BertscheSusanne SchiekThorsten KaiserInes GockelChristoph JostenSirak PetrosPublished in: European journal of clinical pharmacology (2020)
Co-medication of ASA and metamizole significantly influences platelet inhibition with variations during the day and can cause HTPR in patients taking ASA prior to metamizole or simultaneously.