Genetic Liability to Rheumatoid Arthritis in Relation to Coronary Artery Disease and Stroke Risk.
Qiqiang HePaul CarterAmy M MasonFangkun YangStephen BurgessSusanna C LarssonPublished in: Arthritis & rheumatology (Hoboken, N.J.) (2022)
This study found that genetic liability to RA was associated with an increased risk of CAD and ICH and that the association with CAD might be mediated by CRP. The heightened cardiovascular risk should be actively monitored and managed in RA patients, and this may include dampening systemic inflammation.
Keyphrases
- coronary artery disease
- rheumatoid arthritis
- disease activity
- end stage renal disease
- ankylosing spondylitis
- genome wide
- ejection fraction
- newly diagnosed
- percutaneous coronary intervention
- atrial fibrillation
- cardiovascular events
- interstitial lung disease
- prognostic factors
- gene expression
- heart failure
- systemic sclerosis
- subarachnoid hemorrhage
- transcatheter aortic valve replacement
- idiopathic pulmonary fibrosis
- patient reported