ZNNT1 long noncoding RNA induces autophagy to inhibit tumorigenesis of uveal melanoma by regulating key autophagy gene expression.

Peng LiJie HeZhi YangShengfang GeHe ZhangQing ZhongXianqun Fan

Published in: Autophagy (2019)

ADCD: autophagy dependent cell death; ANXA2R: annexin A2 receptor; ATG12: autophagy- related 12; ATG5: autophagy -related 5; ceRNA: competing endogenous RNAs; CQ: chloroquine; iTRAQ: isobaric tags for relative and absolute quantitation; lncRNA: long noncoding RNA; MAP1LC3/LC3: microtubule-associated protein 1 light chain 3; MTOR: mechanistic target of rapamycin kinase; MTORC1: MTOR complex 1; MTORC2: MTOR cmplex 2; PP242: Torkinib; RACE: rapid amplification of cDNA ends; SQSTM1/p62: sequestosome 1; UM: uveal melanoma.

Keyphrases

cell death
long noncoding rna
endoplasmic reticulum stress
signaling pathway
gene expression
oxidative stress
cell proliferation
cell cycle arrest
mass spectrometry
long non coding rna
dna methylation
solid phase extraction
quantum dots
binding protein
gas chromatography