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Technical note: hydrogel-based mimics of prostate cancer with matched relaxation, diffusion and kurtosis for validating multi-parametric MRI.

Dariya I MalyarenkoShigeto OnoTed J E LynchScott D Swanson
Published in: Medical physics (2023)
A stable biomimetic mpMR reference based on hydrogels has been developed with a range of multi-compartment diffusion and relaxation parameter combinations observed in cancerous and healthy prostate tissue.
Keyphrases
  • prostate cancer
  • tissue engineering
  • drug delivery
  • radical prostatectomy
  • hyaluronic acid
  • diffusion weighted imaging
  • magnetic resonance imaging
  • single molecule
  • contrast enhanced
  • extracellular matrix
  • drug release