Myocardial Elasticity Imaging Correlates with Histopathology in a Model of Anthracycline-Induced Cardiotoxicity.
Caroline E MillerJennifer H JordanAlexandra ThomasSarah R FridayGiselle C MeléndezJared A WeisPublished in: bioRxiv : the preprint server for biology (2023)
This methodology can show progressive changes in LV elasticity and has potential to be a more sensitive indicator of elasticity changes than current clinical measures of cardiotoxicity. LV elasticity may provide a valuable biomarker for cardiotoxic effects of anthracycline-based chemotherapeutics and cardiac disease detection.