Kinetics and ability of binding antibody and surrogate virus neutralization tests to predict neutralizing antibodies against the SARS-CoV-2 Omicron variant following BNT162b2 booster administration.

Germain SimonJulien FavresseConstant GillotMélanie ClossetÉmilie CatryJean-Michel DognéJonathan DouxfilsGrégoire WieërsJean-Louis Bayart

Published in: Clinical chemistry and laboratory medicine (2023)

This study showed a significant drop in humoral immunity 6 months after booster administration. Anti-RBD IgG and Omicron sVNT assays were highly correlated and could predict neutralizing activity with moderate performance.

Keyphrases

sars cov
immune response
dengue virus
high intensity
high throughput
binding protein
coronavirus disease