Pharmacokinetic Modeling of Targeted Ultrasound Contrast Agents for Quantitative Assessment of Anti-Angiogenic Therapy: a Longitudinal Case-Control Study in Colon Cancer.

Simona TurcoAhmed El KaffasJianhua ZhouAmelie M LutzHessel WijkstraJürgen K WillmannMassimo Mischi

Published in: Molecular imaging and biology (2020)

USMI (semi)quantitative parameters provide earlier assessment of the response to therapy compared to tumor volume, permit early prediction of non-responders, and correlate well with ex-vivo angiogenesis biomarkers.

Keyphrases

magnetic resonance imaging
magnetic resonance
endothelial cells
high resolution
stem cells
vascular endothelial growth factor
mesenchymal stem cells
contrast enhanced ultrasound