Modeling the natural history of ductal carcinoma in situ based on population data.

Sarocha ChootipongchaivatNicolien T van RavesteynXiaoxue LiHui HuangHarald Weedon-FekjærMarc D RyserDonald L WeaverElizabeth S BurnsideBrandy M Heckman-StoddardHarry J de KoningSandra J Lee

Published in: Breast cancer research : BCR (2020)

Our findings suggest that the majority of screen-detectable but unbiopsied preclinical DCIS lesions progress to IBC and that the MST is relatively short. Nevertheless, due to the heterogeneity of DCIS, more research is needed to understand the progression of DCIS by grades and molecular subtypes.

Keyphrases

high throughput
single cell
electronic health record
big data
cell therapy
single molecule
machine learning
data analysis