Aryl-1,3,5-triazine ligands of histamine H4 receptor attenuate inflammatory and nociceptive response to carrageen, zymosan and lipopolysaccharide.

Szczepan MogilskiMonika KubackaDorota ŁażewskaMałgorzata WięcekMonika Głuch-LutwinMałgorzata Tyszka-CzocharaKarolina Bukowska-StrakovaBarbara FilipekKatarzyna Kieć-Kononowicz

Published in: Inflammation research : official journal of the European Histamine Research Society ... [et al.] (2016)

Our results demonstrate the anti-inflammatory and analgesic activity of the new aryl-1,3,5-triazine derivatives, which are primarily H4R-dependent.

Keyphrases

anti inflammatory
neuropathic pain
solid phase extraction
inflammatory response
toll like receptor
oxidative stress
lps induced
binding protein
liquid chromatography