Login / Signup

Dexmedetomidine Protects Cardiomyocytes against Hypoxia/Reoxygenation Injury by Suppressing TLR4-MyD88-NF-κB Signaling.

Jin-Meng GaoXiao-Wen MengJuan ZhangWei-Rong ChenFan XiaKe PengFu-Hai Ji
Published in: BioMed research international (2017)
DEX pretreatment protects rat cardiomyocytes against H/R injury. This effect is partly mediated by TLR4 suppression via TLR4-MyD88-NF-κB signaling.
Keyphrases
  • toll like receptor
  • nuclear factor
  • inflammatory response
  • lps induced
  • immune response
  • signaling pathway
  • oxidative stress
  • pi k akt
  • endothelial cells
  • high glucose
  • cardiac surgery
  • cell proliferation