Sympathetic Neural Overdrive, Aortic Stiffening, Endothelial Dysfunction, and Impaired Exercise Capacity in Severe COVID-19 Survivors: A Mid-Term Study of Cardiovascular Sequelae.
Diego FariaRenata Moll-BernardesLaura TestaCamila Motta Venchiarutti MonizErika C RodriguesAmanda G RodriguesAmanda AraujoMaria J N N AlvesBruna E OnoJoão E IzaiasVera Maria Cury SalemiCamila J PaixãoGraziela Amaro-VicenteMaria U P B RondonKatelyn R LudwigDaniel H CraigheadMatthew J RossmanFernanda M Consolim-ColomboKátia De AngelisMaria-Claudia IrigoyenDouglas R SealsCarlos Eduardo NegrãoAllan R K SalesPublished in: Hypertension (Dallas, Tex. : 1979) (2022)
Our study revealed that COVID-19 survivors have sympathetic overactivation, vascular dysfunction, cardiac morpho-functional changes, and reduced exercise capacity. These findings indicate the need for further investigation to determine whether these manifestations are persistent longer-term and their impact on the cardiovascular health of COVID-19 survivors.