Anti-Interleukin-23 Autoantibodies in Adult-Onset Immunodeficiency.
Aristine ChengAnuj KashyapHelene SalvatorLindsey B RosenDevon ColbyFatemeh Ardeshir-LarijaniPatrick J LoehrerLi DingSaul O Lugo ReyesSean RimintonMadison BallmanJoseph M RoccoBeatriz E MarcianoAlexandra F FreemanSarah K BrowneAmy P HsuAdrian ZelaznyArun RajanIrini SeretiChrista S ZerbeMichail S LionakisSteven M HollandPublished in: The New England journal of medicine (2024)
Among patients with a variety of mycobacterial, bacterial, or fungal infections, the presence of neutralizing anti-interleukin-23 was associated with severe, persistent opportunistic infections. (Funded by the National Institute of Allergy and Infectious Diseases and others.).