Multiple genetic variants associated with posttransplantation diabetes mellitus in Chinese Han populations.

Jie ChenLixin LiYunfei AnJunlong ZhangYun LiaoYi LiLanlan Wang

Published in: Journal of clinical laboratory analysis (2017)

Recipients with STAT4 (rs7574865) T allele are associated with an increased concentration of IL-1β, interferon-γ, monocyte chemoattractant protein, and macrophage inflammatory protein-1b. The genetic variants of STAT4 (rs7574865) and IL-18 (rs1946518) may be new important markers for PTDM.

Keyphrases

dendritic cells
cell proliferation
protein protein
amino acid
adipose tissue
oxidative stress
endothelial cells
immune response
kidney transplantation
genetic diversity