Galectin-3 enhances atrial remodelling and arrhythmogenesis through CD98 signalling.

Wan-Li ChengYao-Chang ChenShao-Jung LiTing-I LeeTing-Wei LeeSatoshi HigaCheng-Chih ChungYu-Hsun KaoShih-Ann ChenYi-Jen Chen

Published in: Acta physiologica (Oxford, England) (2022)

Gal-3 recombinant protein administration increases atrial fibrosis and arrhythmogenesis through CD98 signalling. Targeting Gal-3/CD98 axis might be a novel therapeutic strategy for patients with AF and high Gal-3 levels.

Keyphrases

atrial fibrillation
nk cells
left atrial
cancer therapy
protein protein
mitral valve
amino acid