Covid-19: contribution of clinical characteristics and laboratory features for early detection of patients with high risk of severe evolution.
Edith SepulchreGuillaume PittieVioleta StojkovicGentiane HaesbroekYves CramaMichaël SchynsHenry ParidaensJerôme de MarchinStéphane DegesvesChristian BiemarSandrine BoccarJean-Marc SenterreJean-Marc MinonPublished in: Acta clinica Belgica (2020)
This Belgian study revealed clinical and laboratory features able to predict high risk of ICU requirement, or even death, at admission time. These results provide a potential tool for patient's triage in a context of pandemic.Abbreviations: COVID-19: coronavirus disease 2019; ARDS: acute respiratory distress syndrome; DIC: disseminated intravascular coagulopathy; MOF: multi-organ failure; RT-PCR: real-time reverse transcription-polymerase chain reaction; UFE: unfavorable evolution; ICU: intensive care unit; EDTA: ethylenediamine tetraacetic acid; WBC: white blood cell count; Hb: hemoglobin level; PCT: procalcitonin; Na: sodium; K: potassium; PT: total protein, CRP: c-reactive protein; Cr: creatinine; ALAT: alanine aminotransferase; ALAT: aspartate aminotransferase; TB: total bilirubin, LDH: lactate dehydrogenase, FERR: ferritin; hs-Tnt: high sensitive-troponin T; cGFR: corrected glomerular filtration rate; QR: quick ratio; DDIM: D-dimer; FIB: fibrinogen; SD: standard deviation; IQR: interquartile ranges; ROC: receiver operating characteristics; ECMO: extracorporeal membrane oxygenation; NLR: neutrophil to lymphocyte ratio; AUC: area under the curve; BMI: body mass index.
Keyphrases
- coronavirus disease
- acute respiratory distress syndrome
- extracorporeal membrane oxygenation
- mechanical ventilation
- intensive care unit
- body mass index
- emergency department
- respiratory failure
- sars cov
- single cell
- respiratory syndrome coronavirus
- weight gain
- case report
- cell therapy
- physical activity
- coronary artery
- mycobacterium tuberculosis
- transcription factor
- early onset
- weight loss
- metal organic framework
- risk assessment
- mesenchymal stem cells
- stem cells
- liver fibrosis
- amino acid
- red blood cell