The late effects of haematopoietic stem cell transplants in paediatric patients: a 25 year review.
Samantha Lai-Ka LeeQuynh-Nhu NguyenCindy HoSimon JamesAmreeta KaurAngelina LimKarin TiedemannMargaret ZacharinPublished in: The Journal of clinical endocrinology and metabolism (2024)
We confirm gonadal dysfunction, multiple endocrine and metabolic abnormalities, thyroid cancer and SMNs, as common sequelae of HSCT, and identify gaps in management - particularly the need for informed fertility counselling and pretreatment fertility preservation, evaluation and management of bone health, and underline need for early lifestyle modification, long-term surveillance, and prospective planned studies aimed at reducing complication risk.
Keyphrases
- stem cells
- public health
- end stage renal disease
- ejection fraction
- healthcare
- chronic kidney disease
- newly diagnosed
- emergency department
- intensive care unit
- cardiovascular disease
- metabolic syndrome
- bone mineral density
- weight loss
- type diabetes
- mesenchymal stem cells
- risk assessment
- patient reported outcomes
- childhood cancer
- smoking cessation
- young adults
- postmenopausal women
- bone marrow
- human health
- social media
- men who have sex with men