Orexin-1 receptor signaling within the lateral hypothalamus, but not bed nucleus of the stria terminalis, mediates context-induced relapse to alcohol seeking.

Erin J CampbellMitchell Kri HillXavier J MaddernShubo JinTerence Y PangAndrew J Lawrence

Published in: Journal of psychopharmacology (Oxford, England) (2020)

Our results suggest a role for the orexin-1 receptor system in context-induced relapse to alcohol-seeking. Specifically, intra-lateral hypothalamus orexin microcircuits contribute to alcohol-seeking.

Keyphrases

mental health
high glucose
diabetic rats
alcohol consumption
drug induced
endothelial cells