Mogamulizumab Treatment Elicits Autoantibodies Attacking the Skin in Patients with Adult T-Cell Leukemia-Lymphoma.

Yui SuzukiMasato SaitoToshihiko IshiiItaru UrakawaAsuka MatsumotoAyako MasakiAsahi ItoShigeru KusumotoSusumu SuzukiMasanori HiuraTakeshi TakahashiAkimichi MoritaHiroshi InagakiShinsuke IidaTakashi Ishida

Published in: Clinical cancer research : an official journal of the American Association for Cancer Research (2019)

Mogamulizumab elicits autoantibodies playing an important role in skin-related AEs, possibly associated with regulatory T-cell depletion. This is the first report demonstrating the presence of skin-directed autoantibodies after mogamulizumab treatment.

Keyphrases

systemic lupus erythematosus
soft tissue
acute myeloid leukemia
diffuse large b cell lymphoma
young adults