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Autophagy regulates bone loss via the RANKL/RANK/OPG axis in an experimental rat apical periodontitis model.

Zhiwu WuShaoying DuanMingming LiAopeng ZhangHui YangJingjing LuoRan ChengTao Hu
Published in: International endodontic journal (2024)
Autophagy may exert a protective effect against AP by regulating the RANKL/RANK/OPG axis, thereby inhibiting excessive bone loss.
Keyphrases
  • bone loss
  • signaling pathway
  • oxidative stress
  • cell death
  • endoplasmic reticulum stress
  • transcription factor
  • weight gain
  • inflammatory response