Time-dependent changes in feeding behavior and energy balance associated with weight gain in mice fed obesogenic diets.
Payam A FathiMichelle B BalesJulio E AyalaPublished in: Obesity (Silver Spring, Md.) (2024)
Exposure to obesogenic diets engages homeostatic regulatory mechanisms for ~2 weeks that ultimately fail, and consequent weight gain is characterized by impaired satiation and satiety. Insights into the etiology of obesity can be obtained by investigating changes to satiation and satiety mechanisms during the initial ~2 weeks of HFD exposure.