Abdominal Lymphadenopathies: Lymphoma, Brucellosis or Tuberculosis? Multidisciplinary Approach-Case Report and Review of the Literature.
Antonio MirijelloNoemi RitrovatoAngelo D'AgrumaAngela de MatthaeisLuca PazienzaPaola ParenteDario Pio CassanoAnnalucia BiancofioreAngelo AmbrosioIlluminato CarosiEttore SerricchioPaolo GrazianoFrancesca BazzocchiPamela PiscitelliSalvatore De CosmoPublished in: Medicina (Kaunas, Lithuania) (2023)
Abdominal pain represents a frequent symptom for referral to emergency departments and/or internal medicine outpatient setting. Similarly, fever, fatigue and weight loss are non-specific manifestations of disease. The present case describes the diagnostic process in a patient with abdominal pain and a palpable abdominal mass. Abdominal ultrasonography confirmed the presence of a mass in the mesogastrium. Computed Tomography (CT) and Magnetic Resonance Imaging (MRI) scans oriented toward calcific lymphadenopathies with increased metabolism in the positron emission tomography-computed tomography (PET-CT) scan. Laboratory examinations were inconclusive, although serology for Brucella and the Quantiferon test were positive. After multidisciplinary discussion, the patient underwent surgical excision of the abdominal mass. Histological examination excluded malignancies and oriented toward brucellosis in a patient with latent tuberculosis. The patient was treated with rifampin 600 mg qd and doxycycline 100 mg bid for 6 weeks with resolution of the symptoms. In addition, rifampin was continued for a total of 6 months in order to treat latent tuberculosis. This case underlines the need for a multidisciplinary approach in the diagnostic approach to abdominal lymphadenopathies.
Keyphrases
- computed tomography
- positron emission tomography
- magnetic resonance imaging
- contrast enhanced
- pet ct
- abdominal pain
- dual energy
- case report
- weight loss
- mycobacterium tuberculosis
- image quality
- emergency department
- pet imaging
- primary care
- adverse drug
- depressive symptoms
- gestational age
- sleep quality
- quality improvement
- diffusion weighted imaging