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Synergistic phototherapy of NIR wavelength xanthene-quinoline salt-based heavy-atom-free photosensitizers for tumor therapy.

Long HeLin-Hui HeHuan-Hua LaiShuai XuJiao-Liang WangJun-Chao XuLing ShiLin Yuan
Published in: Chemical communications (Cambridge, England) (2023)
We propose a practical strategy to design a series of heavy-atom-free synergistic phototherapy agents (CSQs) with both photodynamic therapy (PDT) and photothermal therapy (PTT) under NIR wavelength excitation by simply replacing the indole salt of xanthene Changsha (CS) with quinoline salt.
Keyphrases
  • photodynamic therapy
  • fluorescence imaging
  • molecular dynamics
  • molecular docking
  • cancer therapy
  • stem cells
  • mesenchymal stem cells
  • bone marrow
  • molecular dynamics simulations